Most likely there's invalid/non-existent directory in the computers PATH environment variable. See Re: Invalid Path or File Name running Exe Message #1010887

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>I have a problem site where our apps used to run but now no longer do. The user claims "nothing has changed" :) Anyway, after trying a few things and always getting the same result we wrote a one line program to display a messagebox() only. Compiled to exe and tried to run it. Same result - a message box pops up (not ours) with title "Program Error" and message "Invalid path or file name". Buttons Cancel, Ignore, and Help. None of these help - the program crashes with c5 error.
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>The VFP8 dll's are in the app folder itself. Have tried clean re-install but no luck. Have searched for other copy's of the VFP dll but they do not exist anywhere on the users machine.
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>I have suggested to the user and his tech support that they need to switch off all auto-run apps and test again. Re-load each auto-run app one by one until the program stops working. The user is running AV and has anti-spyware. All the usual suggestions have been made like turning off the AV but to no avail. I thought I would put it out here on the UT for any other possible suggestions.
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>Thanks