What does the test below return? You don't have any buffering turned on or anything like exclusive = ON in the config.fpw, right? Is multilocks on or oFF?

SET REPROCESS TO 5 SECONDS
SET EXCLUSIVE OFF
SET MULTILOCKS ON
SELE 0
USE CDM05RPM     && hope name is correct
IF USED("CDM05PRM") .and. !EOF("CDM05PRM") .and. recno("CDM05PRM") > 0
   WAIT WINDOW "Last number used was: " + ALLTRIM(STR(MEMLASTWO))+ ".  Press anykey to lock record ..."
   IF RLOCK() 
      WAIT WINDOW "Locked record successfully. Press anykey to get new value..."
      IF !EMPTY(MEMLASTWO)
         new_wo = MEMLASTWO + 1
      ELSE
         new_wo = 1
      ENDIF
      REPLACE NEXT 1 MEMLASTWO WITH new_wo
      REPLACE NEXT 1 MEMLASTRR WITH new_wo
      unlock
   ELSE
      wait window "Unable to lock record to get next wo number. Press anykey..."
   ENDIF
ELSE
   WAIT WINDOW "Unable to open CRM05RPM.  Press anykey..."
ENDIF
IF USED('CDM05RPM')
   USE IN CDM05RPM
ENDIF