I thought I posted the code I needed... Well, let's see... here is how I populate the combobox:

Dim activityDV As New DataView(gParmsDS.Tables("parms"))
activityDV.RowFilter = "parm_type = 'activity'"
cboActivity.DataSource = activityDV
cboActivity.DisplayMember = "short_desc"
cboActivity.ValueMember = "parm_id"

Here is the line binding the combobox to my datasource:

cboActivity.DataBindings.Add(New Binding("SelectedItem", regDV, "activities"))

And I am calling a web service to update my datasource. What other code do you feel I should post? Thanks!