The Config.fpw is a configuration file so you cannot use any VFP expressions in it but you can call a program using

COMMAND=DO MyStartupProgram
OR
_STARTUP=MyStartupProgram

In addition, SYS(2023) is VFP temp directory so assigning its value to TMPFILES, e.t.c, even if possible, wouldn't change anything.

>Can I use the following commands in config.fpw
>
>command = SYS(3050, 1, 512*1024*1024)
>command = SYS(3050, 2, 512*1024*1024)
>TMPFILES=SYS(2023)
>SORTWORK=SYS(2023)
>PROGWORK=SYS(2023)
>