>Response.Redirect() normally triggers a BeginRequest() - try it in the Page_Load() of Default.aspx as a test. Maybe something in the framework affecting it?

You are right. After verification, BeginRequest() is fired at every hit. What is not fired is the PreRequestHandlerExecute() event and this is where it causes me a problem. In the PreRequestHandlerExecute() event, I have this:

        Dim loPage As System.Web.UI.Page = Context.Handler
        LXFramework.oPage = loPage

It is very important that this is executed at every hit. On a redirect it is not thus my framework has not initialization to the redirected page and worst, it has the oPage reference to the page that did the redirect which can produce unexpected result in the framework logic.