It's a tough nut to crack and very little you can do about it right now. See
http://www.markusegger.com/Blog/Development.aspx?messageid=1f7ddedd-89e0-4f84-aad5-ccb4935a1251

>Hi
>
>Many of my customers have been upgrading to new 19inch LCD screens. The default screen resolution for crips clear text is usually too small for some people so they have been changing the DPI setting on the LCD screen from the standard 96dpi to values up to 144dpi. The do this because decreasing the screen resolution produces fuzzy text.
>
>The net result is that now some of my screens which were designed for 800x600 have controls that no longer align properly. Labels now overlap textboxes or extend past the edge of the form. Is anyone else having this problem? Does anyone have a suggestion about how this can be handled without re-designing all the forms?
>
>For now I have asked the customers to restore the 96dpi setting until I investigate a better solution.
>
>Thanks,
>Simon