>Make sure ASP.NET is enabled. You have to enable the ISAPI extension in the Extensions section of the Web configuration.
>
>By default ASP.NET is disabled...
>
>If that's not it check and make sure that the ASPX (etc.) script maps are installed. If not run
>
>ASPNET_IISREG.EXE -i from the .NET Framework 2.0 directory to register ASP.NET with teh default web site. Look for the command line options to configure other subsites.

Cache ISAPI extensions is checked. Is that the option you are making a reference to?

All the aspx script maps seems to be there.

ASPNET_IISREG.EXE does not exist in c:\windows\microsoft.net\framework\v2.0.50727.