FWIW: having considered its millions of small business customers, the accounting giant Intuit selected SQL Anywhere for its newer versions of Quickbooks. There was still a big technical backlash from customers whose old Quickbooks worked fine with its local database but who experienced trouble with the new improved C/S version.
IMHO people are well advised to consider their customers very carefully before applying any blanket ideology, including database selection.
"... They ne'er cared for us
yet: suffer us to famish, and their store-houses
crammed with grain; make edicts for usury, to
support usurers; repeal daily any wholesome act
established against the rich, and provide more
piercing statutes daily, to chain up and restrain
the poor. If the wars eat us not up, they will; and
there's all the love they bear us."
-- Shakespeare: Coriolanus, Act 1, scene 1
