A connection string could not be found in the application configuration file for database key 'CAIDEV2'

at OakLeaf.MM.Main.Managers.mmDatabaseManager.GetConnectionString(String databaseKey)
at OakLeaf.MM.Main.Business.mmBusinessObject.GetConnectionString(String databaseKey)
at OakLeaf.MM.Main.Business.mmBusinessObject.GetDataAccessObject(String databaseKey)
at OakLeaf.MM.Main.Business.mmBusinessObject.GetDataAccessObject()
at OakLeaf.MM.Main.Business.mmBusinessObject.GetAllData()
at Coalition.Gemini.ProviderMatching.Business.EDIPicker.EDIPicker..ctor()
at Coalition.COMPASS.PM.EDIPPProcessor.ProcessClaimBatch(Int32 BatchID)

It runs fine when not in COM+ mode but throws this error as soon as it is run in COM+ mode.

Anyone seen a simialr issue before?