>>>We are attempting to make an automatic backup application. The application zip up files, and send the zip to server across the internet. Logic tells me the best way is to use FTP. But the client refuses on agree. They want to create drive mapping and simply copy the backup to the server. I never knew this could be done. How would one do this?
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>>Establish a VPN connection to the server?
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>Yes, I see. But can this be done progammatically? The backup are going after the store are closed.

Tell your client you can do that, but if you open that up, you open a known security risk. FTP has better error checking than trying to send via http, since it has some. If they still want to do it, expose their hard drive with a drive share (get a written disclaimer signed in blood before doing this), then from the client you can simply use the net use command. From a dos/cmd prompt issue something like the following:

net use x: /delete && delete any current mapping to that drive
net use x: \\192.168.1.100\stupidclientbackupfolder /user:username passwordgoeshere

Of course, you have the issue of firewalls getting turned on, etc on the target, which can stop things. I'd recommend telling the client, you can do the same thing via ftp, without turning on netbios names across the internet. Then again, why not just throw it open and go to a warez site and double-dog dare em!