I ran into this for a client... Their server had the IIS set to .Net 1.1. I since rebuilt a project under .Net 2 and got a similar message... To Fix, I Googled the System.web.... portion and found (which can't find again), but here's what I had to do...

Open IIS.
Expand treeview to default website... Right-click - properties.
Click on the ASP.NET tab of pageframe. Change the drop-down for ASP.Net version from 1.1 to 2.0.
Save and exit.

Then, just for grins, I did a DOS prompt and
net stop w3svc
net start w3svc
to allow the service to be cleared and restarted... The project ran fine after that.






>I'm getting the following error message.
>
>

>System.Web.Hosting.HostingEnvironmentException: Failed to access IIS metabase. The
>process account used to run ASP.NET must have read access to the IIS metabase (e.g.
>IIS://servername/W3SVC). For information on modifying metabase permissions, please see
> http://support.microsoft.com/?kbid=267904.
>

>
>I tried to follow the instruction found on the link with no success.
>
>Has anyone worked with metaacl? If so, any hint is very much appreciated?
>
>TIA