Sorry, I misunderstood your initial question.
You could go by either of two ways:
1.Try to use DDE link. Frankly, I didn't try it for millenium.
2.Modify 2nd application code so it will update records in certain table keeping track of open forms; 1st app. may check the table.

>If i am in the 1st EXE program and know the 2nd one is running, how can I get reference to the _Screen.Forms collection in the 2nd EXE?
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>>>From one VFP exe program running, i can determine if another VFP application is running on the workstation. If this is true is there a way to determine if a particular form is open in that 2nd application?
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>>>Problem I have is that application 1 can be making changes and application 2 could cause conflicts based on what is being done. I need to notify that the second application's particular form is open.
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>>>Thanks in advance
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>>You should scroll through _Screen.Forms collection checking for particular form name.