>>Yes, I would think so. I was unable to run another recommended tool - SuperAntiSpyware - it produced an error. There is some strange popup appearing every minute or so saying about security alert and trying to go online to some site.
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>Have you tried booting into safe mode first? If that does not work then you might need to put this drive as a slave drive to a clean machine and clean the infected drive from the clean machine (or just salavge what data/docs need to be saved and then wipe the hard disk and do a clean O/S reinstall).

I'll try booting into safe mode if I can figure this out. The rest of your suggestions is a bit hard for me, so if first would not work, we'll may try to ask some external help.