>I would like to run a query with a VPF desktop application that would generate a list of addresses that could then be used to create multiple Markers on a Google Map. I would want it to Geocode and populate the map in as little clicks of the button as possible.
>
>Has anyone done this before?
>
>Can anyone point me in the right direction?

Yes, I have. Which part do you have trouble with?
There a many samples here:
http://code.google.com/apis/maps/documentation/demogallery.html