Disclaimer: I have no reasons to link this error message to MM Framework.

For several days for not yet identified reason MM ASP.NET (VB, SQL Server 2005) application keeps slowing down during a day until complete halt.

Eventually users start to receive this message (the application halts):

Timeout expired. The timeout parameter elapsed prior to completion of the operation or the server is not responding.
The statement has been terminated.

The application is used daily by 30 to 40 concurrent users, and is kept in present configuration for more than 12 months. The last time the application got a minor update was about a month ago, several weeks prior to this issue first got noticed.

Again, I have no reasons to link this error message to MM Framework. But does this message ring any bell? Whoever experienced something similar recently or some time ago, your help and advice is greatly appreciated.

Thank you!