>>Glad you got it sorted.
>>
>>If you've tried all 3 of the products you mentioned, and they didn't fix it, the only thing left is to reformat and reinstall everything from scratch. But if your customer has moved to a Mac and doesn't need to use the PC anymore, maybe you don't have to bother.
>>
>
>Maybe one more thing to try: ComboFix

Have you had success using that, where the other ones failed?

I think my biggest concern is, basically, that a computer be trustworthy. These days, if any malware finds a crack in your defenses to load itself, it loads a whole smorgasbord of associated crap. Does any single antimalware product, or even a group of them, fix all that? How can anyone be sure?

Just one recent example, a lot of people didn't realize they were compromised until they tried to install a certain Windows update: http://blogs.technet.com/b/msrc/archive/2010/02/17/update-restart-issues-after-installing-ms10-015-and-the-alureon-rootkit.aspx

So, if you get infected, you can:

1. Reformat and reinstall from scratch (recent image backups help a lot here):

+ guaranteed successful removal of malware
+ system is known trustworthy afterwards
- could take a while if you don't have good backups
- could lose some data or settings if no image backup available

2. or, try to remove the infection(s):

+ may be quicker if standard tools can identify the problem(s)
+ may preserve some data and settings that could be lost with a reformat/reinstallation
- may NOT be quicker than restore of a known good image
- no guarantee of success
- is computer really trustworthy afterwards?

BTW I think you should smack Bono for so blatantly ripping off your style ;)