>>>I have seen messages about this before, but can't find them. On some machines lo = Createobject('outlook.application') fails, even though Outlook 2010 is installed. Any tips?
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>>Does this machine use Office 2010 64 bit?
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>>http://social.msdn.microsoft.com/Forums/en/visualfoxprogeneral/thread/3d42a63d-1d38-4c36-b503-399742473079
>>
>>http://social.msdn.microsoft.com/Forums/en-US/visualfoxprogeneral/thread/ea1123a8-e5ea-4be7-b2da-4277477fc4e4
>
>No, that's one of the first things I checked. Office is 32-bit. We have several other machines where we don't have this problem. We have tested on machines running both Win7-32 and Win7-64, and have over all no problem. But one a few machines, with the same stup, we don't manage to "connect" to Outlook (32-bit).

Maybe a permissions issue? Do you see a difference if you run your app as an Administrator?

You might also check the Application Event Log, sometimes there are messages there that can point to the problem.