ClickOnce on the server might be an option?
Possible downsides:
(a) Installation is 'per user' not 'per machine'
(b) Would require full trust to create/write to specific folders.

I have been looking in to Click Once. Installation 'per user' is not an issue as long as there is a link that they can do it from. My app is replacing an old web app that the users did not like, so when we go live, we will just redirect them to the install URL.

The thing that I can't figure out from everything I have been reading is whether or not click once installs the entire app to the user's machine. I want the exe to live on the server and just install the stuff that is required for them to run it.

-- Marcia