>>>Any advice gratefully received!
>>>
>>
>>Are you sure you need a native application? Have you considered ASP.NET MVC with C#?
>>
>>It's a really, really nice implementation of MVC and because the interface is a browser, making it tablet/phone compatible is much, much simpler. Not to mention it will work on Mac's too.
>
>Are you sure about the Mac? The architecture is definitely extensible but I didn't know ASP.NET MVC with C# works on the Mac.

Works on Mac from the client side. The point I was trying to make is that anything with a browser can access an internet app. Obviously the server would need to be a MS machine with this setup.

One of our favorite in-house applications (FogBugz) runs on IIS/ASP with SQL Server

A recent free-trial we installed was the same thing IIS/ASP with SQL Server

We're seeing more and more IIS/ASP + SQL Server apps because that means 1 server install an no install on the client machines. This also gives the flexibility of making it internet accessible or just in-office.