>>>If you've separated the app into tiers nicely, you can wrap the back end in web services and rewrite the UI in HTML5/JavaScript, which can then compile into most mobile devices.
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>>In other words, no :)
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>>You also need to determine if the application requires local storage - this ups the challenge factor.
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>But suppose the application does not require a local storage and all data processing is done on the server, do you think ASP.NET with HTML5 is a good approach for, say iPad?

Yes. The iPad browser (safari) seems to render standard asp.net sites pretty well. Not mac pretty, but it works.

I'm actually doing one now that is ASP.NET that will (hopefully) handle IE and firefox desktop along with iPad. I'll be doing a few iPad specific pages that will reduce what is displayed, but for the most part it will be common pages for the real world and iPads.