I guess the only way would be to set a property when I know I can fill the dataset:

                        Using loSQLConnection As New SqlConnection(cConnectionString)
                            oCommand.Connection = loSQLConnection
                            nResult = oDataAdapter.SelectCommand.ExecuteNonQuery()

                            ' If we can fill
                            If lDataSet Then
                                oDataAdapter.Fill(oDataSet)
                            End If

                        End Using

Is there something simpler than that I can use to avoid setting up a property?