>>I have Office 2010 x64 too, and it works fine for me. Perhaps there was an option to install the drivers when I originally installed Office. I don't remember. Try this: Create an empty file with a .UDL extension, double-click on it and look at the Providers tab. You should see Microsoft Office 12.0 Access Database Engine OLE DB Provider. If it's not there, download the drivers from http://www.microsoft.com/download/en/details.aspx?id=13255.
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>It is there. What should I do on the Connection tab? This is what it shows (see attached). I try to put xls file name in the Data Source (with the path) and got an error.
>
>I also just re-installed this driver and I am still getting errors.

Hmmmm... I don't know. Do you see C:\Program Files (x86)\Common Files\Microsoft Shared\OFFICE14\ACEOLEDB.DLL on your system? Notice that it is in the 32-bit (x86) folder. If it's there, maybe try to register it.