On 64-bit OS, try running WScript.exe not from C:\Windows\System32 but from C:\Windows\SysWOW64

File System Redirector
http://msdn.microsoft.com/en-us/library/aa384187.aspx
http://support.microsoft.com/kb/942589

...32-bit applications can access the native system directory by substituting %windir%\Sysnative for %windir%\System32. WOW64 recognizes Sysnative as a special alias used to indicate that the file system should not redirect the access...

This is how a similar issue with invoking on-screen keyboard from VFP on 64-bit OS can be resolved:
http://www.news2news.com/vfp/?example=582