>When you look at a clock, do you change what time it is?
>I get what you're saying, observation collpases the waveform.
>But that doesn't make anything worthless. That seems to be an unnecessary claim.

It changes it, but as you say, not enough to matter for the normal operation of a clock. For simulated human beings ... they would operate at the macro level as we do. While they're there, they are affecting everything around them appropriately at the quantum level ... but as for trees, and birds, and bridges, and toothpaste ... it would not be an interference beyond use.