I have never installed XAMPP before but there is no reason why you can't run WordPress on IIS. You just need to install Fastcgi on IIS. Here is an option.

http://techsugar.wordpress.com/2011/03/02/how-to-install-wordpress-on-iis-7-5-using-sql-server-2008/

Installing PHP and mySql without using XAMPP is not that difficult. The php installer can install fastcgi for you.

>Hi,
>
>I want to install XAMPP so that I can then install WordPress on my Windows 7 PC. Most of the work I do on the PC is with VS, IIS and SQL Server (and VFP of course).
>
>Could I run into a conflict with XAMPP (MySQL and PHP) running along with IIS on the same PC?