>Anyone found that before? You have a Windows Update that asks for a reboot. But, you do not reboot right away because you have 25 opened windows and projects and you need all that to remain as is. Then, you hope to reach the weekend, to reboot, and get a new start. However, the more you wait, the more your PC gets slow. This is the 3rd time I have observed that. Otherwise, I can work for weeks without a reboot and all is ok. But, when there is a pending reboot, it is doing that.
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>...and this is when you see the ad on TV "My Clean PC". Geez, this guy is scary! :)

I tend to set the Windows Update to at most notify rather than automatically download or install. This gives me the ability to choose the time an update is performed -- that way I'll not be inconvenienced as much. Furthermore, when I do choose the update to be performed, I manually select to go to the website directly, rather than have it download in the background -- that way I'm not going to start doing something that will be an inconvenience to stop when Windows wants to restart. I'd found that once Windows wants to restart, it's best to let it restart as soon as possible. The longer you wait, you're apt to experience degraded system performance, or worse -- system instability (and typically it results in restart anyway -- but not in a controlled fashion).