HTML/CSS/JavaScript/jQuery are all very prevalent in ASP.NET MVC. You can use them in tandem. You can also take an extremely heavy JS approach and make single page apps using frameworks like BackboneJS. Ajax calls are easy to maintain in ASP.NET MVC, so even if you do take a heavy JS approach using ASP.NET would still be a good fit - YMMV obviously.

>I don't know the answer (yet) to how you get data in and out, which is obviously a requirement in any serious business app. Where I am coming from is that there is clearly a lot of momentum behind the HTML/CSS/JavaScript/jQuery approach. If you look at MSDN Magazine lately, Microsoft has started mentioning JS right alongside C# and VB.NET. TypeScript is helping some traditional .NET developers get over their heebie jeebies at JS's lack of strong typing and classes. At a Code Camp here a few Saturdays ago there were quite a few sessions on topics like jQuery UI, TypeScript, and how to make your JS pages load faster. All of these were very well attended. (And so you don't think this was some open source freakfest, there was also a session on best practices in testing ASP.NET MVC apps, also well attended).
>
>I probably did not express myself well to Dmitry. Actually I'm pretty sure I didn't. I was not advocating the HTML/CSS/JavaScript/jQuery approach over the web tools in .NET, just saying he might consider it as an alternative. He made it clear he is comfortable with C# and staying with the .NET web tools, it's just a question of which one. Which is fine. I am not trying to tell anyone what to do and do not have deep enough knowledge of any of this stuff to speak with any authority. At this point my knowledge is "a mile wide and an inch deep" ;-)
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>>What's serving up your data?
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>>>Yes, enough to be dangerous. I was just suggesting an alternate approach which I have become interested in lately.
>>>
>>>>Have you looked at MVC?
>>>>
>>>>
>>>>>Or he could go with a totally non-.NET solution of HTML/CSS/JavaScript/jQuery. But Dmitry has been drinking water from a fire hose already lately and probably isn't interested in taking on another bunch of tools ;-)