>>It still matters a lot because serious lockins still exist.
Yep. In a world of IT commodity, niches will persist just as OS/2 niches persisted for a decade... but without the huge rump of generalized IT taxpayers to support it, the "center cannot hold" against other vendors earning a bomb from smartphone sales or advertising.
>>CAD or Quark on a tablet?
How about a 21" Android desktop? Announced by HP last week, expected price $399. It also runs Splashtop so you can run Windows apps on it until it no longer matters.
"... They ne'er cared for us
yet: suffer us to famish, and their store-houses
crammed with grain; make edicts for usury, to
support usurers; repeal daily any wholesome act
established against the rich, and provide more
piercing statutes daily, to chain up and restrain
the poor. If the wars eat us not up, they will; and
there's all the love they bear us."
-- Shakespeare: Coriolanus, Act 1, scene 1