>I recently have to output a report to a PDF file. The PDF driver is GAAIHO PDF. But when the report generates the output, I am prompted for the destination for the file. Is there a straight forward way to predefine the destination of the file, and not require user interaction. This application is ran without user interaction.

Have you tried FoxyPreviewer? It's free, and you only need to change one or two lines of code.