LOL. FWIW: on April 1 in the late 1990s one of my guys sneaked a little app into an upgrade that mimics a CD c: [lf] delete *.* in command window. Very realistic- causes concern even when you know it's a prank (or is it?!)
More recently I've watched a customer's IS person struggle with Explorer's imaginative hover behavior in Windows 7. Hesitations, hovers or prolonged right-clicks sometimes expand the file tree or suddenly change locale so your intended command executes in the wrong place. Easy to click OK in the resulting dialog if you're in a hurry or not paying attention. He only wiped out the user documentation folder that was easy enough to recover but you can see how easily this sort of thing can occur.
"... They ne'er cared for us
yet: suffer us to famish, and their store-houses
crammed with grain; make edicts for usury, to
support usurers; repeal daily any wholesome act
established against the rich, and provide more
piercing statutes daily, to chain up and restrain
the poor. If the wars eat us not up, they will; and
there's all the love they bear us."
-- Shakespeare: Coriolanus, Act 1, scene 1