I try:

.Container
{}
.Item
{
   float:left;
   vertical-align: top;
}
.Item2
{
   display: block;
   margin-left: 20%;
}

>I have a test page at http://jsfiddle.net/WcHEc/36.
>
>This is a sample container with two divs. The first one is fixed. For now, it only includes "Small text small text". The second one has to take as much space as possible until it wraps. To make it wrap, percentage approach is used. So, the text resizes as required, and then, it wraps.
>
>What I need is all that but to have the second div to take as much space as possible before it wraps without being forced to add a percentage.
>
>Anyone would know the best technique?