>The other thing I'm worrying about is when moving windows into place and maximizing them. With 6 separate monitors, it is easy as each monitor is recognised as such, but with only one monitor serving as 4HD monitors, I'm afraid it will become a mess real quickly. Perhaps there is a tool that could turn a 4HD monitor into 4xHD monitors logically. I'm not aware of such tool though.

Consider https://github.com/microsoft/PowerToys Look up FancyZones. Works like a charm for me. Dell has something similar, but not as good.