>Hello all,
>
>My application is available as a web app. I have a windows server 2016 machine available in the public cloud. I'd like to play wav files depending on what needs to be played.

If you say „web app“, does it run in a browser? If so, it's just the same multimedia stuff as it always was, except you don't have to post a link to your sound file, but rather play it from something's onClick() method.
If it's anything like Citrix or other remoting... well, it depends on the connecting client. I've seen various features that we take for granted locally to be absent in remoting. But then that was a few ages ago, when the bandwidth was the limitation (or, in case of some M$ servers, they never solved the problem of „which app owns the sound at the moment“ so they removed it altogether, this is a server, not an entertainment box). For that part, let's wait for someone else to chime in.