>>whenever the app calls a function in a 16-bit DLL (registered through FOXTOOLS) it ignores any keypress and mouse clicks that might be occuring at that precise moment. [etc.]
>>
>>Any suggestions ?
>
>I'm no API expert, but my one thought is: what are you using the 16-bit function calls to do? Are there equivalent 32-bit functions you could substitute for them? (OK, it's two questions, but it's one thought.)

There is a newly released 32-bit version of the API I've been using, and I plan to try it out asap. FYI, the API enables communication with the SABRE airline reservations system through SABRE's proprietary gateway.