I'm working with Doc-To-Help for a while now, and if you are used in MS Word, it will help you to create professional help very fast and this for all different platforms (from Win3.1 to compiled HTML) in one shot, complete with printed manual.
The price is OK, IMHO, $495,- for the standard version (4.0).
You can get an evaluation copy by
www.wextech.com
Christian Isberner
Software Consultant