Check out the article section for "VFP vs Access". For desktop databases, VFP should be able to do this the quickest. Of course this depends on exactly what you are doing.

>I've recently been asked a question regarding the performance of VFP versus other software. We are processing about 300,000 transactions of data each month (approx 80mb) on a dual Pentium III processor with a SCSI hard drive and about 500mb of RAM.
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>I prefer to use VFP6 as I believe that (in terms of PC applications) it is probably the quickest around - but would like to find out what else there is, and how VFP6 compares.