>When the user clicks to close the active form, I would like to prompt to save changes if any have been made to the current record. My close button is already aware of changes, and deals with the situation accordingly, but can I prevent the form from closing after the user clicks the 'x', if he/she selects cancel from the resulting messagebox?
>Restated: once the user clicks to close the form, can I negate that action?

this calls (i think) the form destroy event. put the code in there to check and cancel form closing if necessary.