The software is designed as a stand-alone. And something like 98%+ of the machines/networks we put it on though don't have problems.

I guess I don't see where I can test it since our application never even starts when we have this problem. Clicking on the icon does nothing. Unless the system has been booted without being plugged into the network..then it works fine. Rebooting with the cabling attached..nothing. And since it works on most NT networks, rather than not working on them, it isn't something conflicting with the generic NT systems..:(