>Hi, All!
>
>We want to distribute some stuff on CD-ROM.
>
>We want to pop up a messagebox saying to read the READ.ME file the first time they put the CD-ROM in their computer.
>
>Any good ideas on how to do this?

Write a value to the registry indicating the install has run before, and if it's not there, fire up READ.ME with Notepad/

Since there's no way to write to the CD, you have to use a local store of soime sort.