>I have developed an application and is used by a number of clients and multiuser. One of my client has a complaint that the app on the server works fine but loading on a node the app loads very slowly and this has happened recently.
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>I have made him defrag, reinstall the app and all that was obvious but the prob remains.
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>Any ideas

Almost all slowdowns like yours reported on UT were attributed to anti-virus software running on the server or workstation. See mskb#Q304482.