>>>Can these options be set programmatically? The reason I ask is I have several different applications that access to same DBC and use a connection contained in it. I would like each application to be able to set the APP and WSID at runtime.
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>>I don't know for sure but you can try DBSETPROP(< connection name >, "CONNECTION", "ConnectString", < new connection string >).
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>I think that updates the DBC connection object. I'm looking for a way to have the application change the value while it is running without updating the connection object in the DBC.

AFAIK, you cannot change those options after connection is established.