>I have a web service created in VFP which I'm currently debugging. However, after I run the service once or twice, I am unable to rebuild the .DLL without an "In use" message popping up. I have exited VFP, restarted IIS. Is there anything else I can do short of the annoying reboot process?

You may IISRESET /RESTART from the command prompt to restart IIS. That will unload the DLL. This can be automated as well when building the project or from IIS.