I think this is still an unresolved problem. It would be nice if you could 'Unload' like you can with a VFP mtdll called from ASP ...
>Can I unload COM DLLs and EXEs from memory using ASP.NET?
>
>I would like to remove my biztier DLL and reporting EXE from IIS memory before running a month-end routine on the server. I could use IISRESET at the command prompt on the server, but I will be using a shared server and don't want to disturb apps outside of my virtual directory.