Yeah this is one of the evil ones... anyway try looking though this...
http://www.techsupportforum.com/computer/topic/17982-1.html

>It took about two days to get rid of the Puppyboyz hijacker which made its place on a client PC. What surprised me is that the related information about that hijacker is almost related to a single place on the Internet. It seems like the movie "The Core" where the specific content would be controlled. After having tried several removal tools such as Ad-Aware, Spy Sweeper, Spybot, Spy Substract and NoAdware, it took SysClean to get rid of it. That tool is a really good one. Anyone has any additional information to share about that hijacker?