I bet there'll be many of these. Some of mine are:

From "Wild Boys" (and I know I haven't got it quite right) the younger bro says to his older vampire bro something like: "You're a sh!t-suckin' vampire ... and I'm tellin' Mom!"

Of course there's the oft misquoted, "... Sierra Madre": "Badges?! ... We ain't ..."

from the 1970s "the Thing", where the severed head sprouts spider legs and runs across the floor. The dope-smoking guy looks at it and says "You gotta be f***ing kidding!"

One of my faves I just heard watching "Vertical Limit" last week. The hero wants to go up the mountain to save his sister and, of necessity, take some nitroglycerin up with him. One of the other climbers says like:

"Let's get this straight. You're gonna climb the mountain with a pack of nitro on your back, and hope it doesn't get jogged? 100 million sperm and you were the fastest!?"