>>>>>Hi everybody,
>>>>>
>>>>>I need to clean my husband's computer. I'd like to do it from the USB drive. What would you recommend?
>>>>>
>>>>>Thanks in advance.
>>>>
>>>>This product (free version available) has received some good recommendations in the infosec community:
>>>>
>>>>http://www.malwarebytes.org
>>>
>>>Thanks. Somehow it didn't even run last time I tried to run it on the laptop.
>>
>>Difficult to know why that would be but it is not impossible that the malware itself is attacking it.
>
>Yes, I would think so. I was unable to run another recommended tool - SuperAntiSpyware - it produced an error. There is some strange popup appearing every minute or so saying about security alert and trying to go online to some site.

Have you tried booting into safe mode first? If that does not work then you might need to put this drive as a slave drive to a clean machine and clean the infected drive from the clean machine (or just salavge what data/docs need to be saved and then wipe the hard disk and do a clean O/S reinstall).