We use Barracuda Yosemite Server Backup against a couple large SQL Server installations, one of which is being manipulated 24/7. Never had an issue.

>DBA mentions that Red Gate executes on a daily basis at midnight for a full backup and partially during the day. When this is the case, I can no longer execute this:
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>ALTER DATABASE MyDatabase ADD FILEGROUP BusinessTime
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>This is very problematic. This is new as we did not have that structure before.
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>Any Red Gate specialists how there who can confirm me what has to be done in Red Gate configuration to avoid locking on such items?
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>Otherwise, please recommend other backup solutions that would not interfere with the good running of our database product.