After I installed Windows ME I have this problems (I installed ME over W98 SE):

1-The machine hangs if I left running all night, usually it hangs after 3 or 4 hours, the only way to put it at work again is power it off and back on.
2-Some vendors still doesn't have drivers for their equipment, to put a name Creative Labs is still promising drivers for the WebCam Go.
3-I needed to uninstall a PCI to Parallel card, not only because it stop working but it makes an annoying beep. If I go to the Control Panel->System, it has an (x), like if there is something wrong with it, but then it displays "this device is working properly", and "no conflicts"
4-The problem with the clock reappeared
5-After I installed the VStudio.Net Beta, some programs started to work very slow (OK, games) although I'm not running VS.

I recongnize that I should not blame ME for some (or all, I don't know) of the problems, but all started after I installed it, that's why I think it was a big mistake. I blame ME specially for 1, 3 and 4 because they were working fine before

My machine is old, I know, 3 years old. Its an AMD K6-2 with 64 Mb of RAM.

Hugo