>You could call strtran twice:
>REPLACE mymemo WITH STRTRAN(mymemo,'my text','new text')
>REPLACE mymemo WITH STRTRAN(mymemo,UPPER('my text'),'new text')
>but for case of mixed case you should write custom function/procedure/method.

Yes, this is excatly where the problem is. I've found that in some cases, the replace value is mixed.