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>>In case you haven't seen Bob's FoxTalk article, it describes how VFP can send an SQL statement to MySQL via an ODBC driver and TCP/IP. MySQL returns the results as a read-write cursor which is updated and sent back again. Bob recommends a DNS-less approach using SQLstringconnect() to make the connection. Simple stuff that I'm sure is old hat for you.
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>>How compatible would the VFP MM framework be with this approach?

That's basically the way the framework supports SQL pass-through. The framework supports using a "named" DSN connection, but I'm sure you could easily use your own connection string. The server could be SQL Server, MySQL, Oracle, or just about anything else.